Each 5 ml of KONSTILAC syrup contains 3.335 g of Lactulose.


In the colon, Lactulose is broken down by colon bacteria into low molecular weight organic acids. This acid lowers the pH in the colon lumen and increases the volume of the colon contents through an osmotic effect. This stimulates colonic peristalsis and restores stool consistency. Constipation improves, and the physiological rhythm of the colon returns. In cases of brain dysfunction due to impaired blood flow in the intestines and liver, Lactulose works by suppressing decomposing bacteria and promoting the growth of beneficial bacteria, such as Bifidobacterium and Lactobacillus, while potentially pathogenic bacteria, such as Clostridium and Escherichia coli, are inhibited. This helps maintain the balance of intestinal flora.


  • Chronic constipation
  • Portal-systemic encephalopathy, including precoma hepaticum and hepatic coma


For Constipation

Initial Dose Daily Supporting Dose
Adult Severe condition 15 ml, twice a day 15-25 ml
Moderate condition 15-30 ml 10-15 ml
Mild condition 15 ml 10 ml
Children 5-10 years old 10 ml, twice a day 10 ml
1-5 years old 5 ml, twice a day 5-10 ml
< 1 years old 2,5 ml, twice a day 5 ml

For precoma hepaticum and hepatic coma (oral):

  • Initial dose: 3 times a day, 30-50 ml.
  • Maintenance dose: adjusted according to patient needs and diarrhea should be prevented.



Box, botol @ 60 ml

No. Reg. : DBL2108027337A1


Box, botol @ 120 ml

No. Reg. : DBL2108027337A1

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