Zibramax (Dry syrup)

Composition :

Each 5 ml contains Azithromycin dihydrate equivalent with Azithromycin 200 mg


Pharmacology :

  • Azithromycin is a macrolide or azelide with usefulness and cooperation with erythromycin, but has greater activity than erythromycin for gram-negative bacteria such as Haemophyllus influenzae and Moraxella catarrhalis and also has activity for some enterobacteries such as Escerichia coli, Salmonella and Shigella spp.
  • Azithromycin has activity forToxoplasma gondii also

Indication :

  • Lower respiratory tract infection which caused by Haemophillus influenzae, Moraxella catarrhalis or Streptococcus pneumoniae
  • Alternative treatment upper respiratory tract infection are Streptococcal pharingitis/tonsillitis caused by Streptococcus pyogenes in patients who can not use the drug of choice
  • Skin and tissue infection which caused by Staphylococcus aureus, Streptococcus pyogenes or Streptococcus agalactiae

Dosage :

  • Children:

There is no complete data on the use of Azithromycin in children under 6 months of age.

Total doses of 30 mg / kgBW should be administered at a dose of 10 mg / kgBW / day once daily for 3 days, or alternatively, given for 5 days with a dose of 10 mg / kgBW as a single dose on the first day, then 5 mg / kgBW Day 2 – 5.

Azithromycin powder for oral suspension can be given with or without food. Azithromycin suspension should be given in accordance with the dosage as below:

Azithromycin Suspensi 30 mg/kg. Total dose therapy
Body Weight   ( kg ) Administration 3 days Administration 5 days

15 – 25


200 mg ( 5 ml ) once daily on   the day 1 – 3

200 mg ( 5 ml )  on the first day, then 100 mg

(2.5 ml) daily once a day

2nd – 5th


26 – 35


300 mg ( 7.5 ml )  once daily on   the day 1 – 3

300 mg ( 7.5 ml )  On the first day, then 150 mg

(3.75 ml) daily once a day

2nd – 5th




400 mg ( 10 ml ) sekali sehari pada hari 1 – 3

400 mg ( 10 ml )  On the first day, then 200 mg

(5 ml) daily once a day

2nd – 5th

> 45 Doses like adults Dosis seperti dewasa
  • In elderly patients: administration in elderly patients equals the dose administered in adult patients
  • In patients with impaired renal function: In patients with mild to moderate renal impairment (glomerular filtration rate 10 – 80 ml / min): no dose adjustment is required, careful administration should be made when Azithromycin is administered to patients with severe renal impairment (glomerular filtration rate <10 ml / min)
  • In patients with impaired liver function: Taking in patients with mild to moderate liver function diseases, same administration as in patients with normal liver function

Syrup Reconstitution :

Add 8 ml of boiled water, shake for 60 seconds. Once reconstituted, the suspension can be stored for 5 days at a temperature below than 250C without loss of potential meaning. Keep it closed. Do not use for more than 5 days after reconstitution

Presentation and Registration Number :

ZIBRAMAX®  Box, Bottle @ 15 ml; DKL1008015438A1


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