Leomoxyl 500

Composition:

Each LEOMOXYL^® 500 capsule contains Amoxicillin Trihydrate equivalent to Amoxicillin 500 mg

 

Pharmacology:

Amoxicillin is a semi-synthetic penicillin antibiotic with a wide spectrum. For oral use, Amoxicillin is rapidly absorbed in the stomach and intestines. Amoxicillin is active against gram-positive and gram-negative microorganisms, except against the type of Staphylococcus type that produces penicillinase.

Amoxicillin is bound to about 20% by body protein, and its activity is not inhibited by serum. The absorption is as good as empty stomach or filled stomach, resulting in higher serum concentrations than ampicillin. Less than 60% of the amount absorbed will be excreted through the urine. The presence of probenecid inhibits urinary outflow, causing the serum amoxicillin level to increase.

 

Indication:

– Infections of the upper respiratory tract: tonsillitis, sinusitis, laryngitis, otitis media.

– Lower respiratory tract infections: acute and chronic bronchitis, bronchiasectasis, pneumonia.

– Infections of the urinary tract: cystitis, pyelonephritis.

– Infection of the skin and soft tissues: cellulitis, infected wounds, carbuncles.

– uncomplicated gonorrhoeae and non-gonococcal urethritis.

 

Dosage:

Adults and children above 20 kg: 250 mg – 500 mg, 3 times daily.

Children <20 kg: 20 mg – 40 mg / kgBW / day in divided doses every 8 hours.

High doses are given for heavier infections.

For severe renal impairment (creatinine clearance 10 ml / min or smaller) adult dose should not exceed 500 mg every 12 hours.

 

Presentation and Registration Numberg:

LEOMOXYL^® Capsule Box, 10 strips @ 10 capsule; DKL9408002201B1

 

ON MEDICAL PRESCRIPTION ONLY

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