Genicol

Composition :

Each capsule GENICOL^® contains Thiamphenicol 500 mg

 

Pharmacology :

• Thiamphenicol is a broad-spectrum synthetic antibiotic and has strong bacteriostatic activity, but at high doses it also acts as a bactericide.
• Thiamphenicol acts by inhibiting the synthesis of bacterial proteins and in free cell systems by suppressing the activity of peptidyl tranferase enzymes catalyzing the formation of bacterial protein peptide bonds.
• Thiamphenicol can be quickly absorbed through the gastrointestinal tract and diffuse into the tissues of the body well including gallbladder and cerebrospinal fluid over other antibiotics
• The half-life of Thiamphenicol is approximately 2-3 hours, after 24 hours of oral Thiamphenicol administration, approximately 80% – 90% has been excreted through the kidneys largely in unchanged form

 

Indication :

• As the first choice for the treatment of typhus or parathypus
• For severe infections caused by:
  • Salmonella spp
  • influenzae (mainly meningeal meningitis)
  • Ricketsia
  • Lymphogranuloma-psithacosis
  • Gram negative that causes bacteremia meningitis

 

Dosage :

Adult:

• Respiratory tract infection: 500 mg, 3 times daily for 5 days
• Urinary tract infection: 500 mg, 4 times daily for 5 days
• Gastrointestinal tract infection: 500 mg, 3 times daily minimum for 5 days

 

Children: 20-40 mg/kg body weight/day or according to the doctor’s instruction

 

Presentation and Registration Number :

GENICOL^®-500 Box, 10 strips @ 10 capsule; DKL9608005101B1

 

ON MEDICAL PRESCRIPTION ONLY

 

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