Composition :

Each capsule GENICOL® contains Thiamphenicol 500 mg


Pharmacology :

  • Thiamphenicol is a broad-spectrum synthetic antibiotic and has strong bacteriostatic activity, but at high doses it also acts as a bactericide.
  • Thiamphenicol acts by inhibiting the synthesis of bacterial proteins and in free cell systems by suppressing the activity of peptidyl tranferase enzymes catalyzing the formation of bacterial protein peptide bonds.
  • Thiamphenicol can be quickly absorbed through the gastrointestinal tract and diffuse into the tissues of the body well including gallbladder and cerebrospinal fluid over other antibiotics
  • The half-life of Thiamphenicol is approximately 2-3 hours, after 24 hours of oral Thiamphenicol administration, approximately 80% – 90% has been excreted through the kidneys largely in unchanged form


Indication :

  • As the first choice for the treatment of typhus or parathypus
  • For severe infections caused by:
    • Salmonella spp
    • influenzae (mainly meningeal meningitis)
    • Ricketsia
    • Lymphogranuloma-psithacosis
    • Gram negative that causes bacteremia meningitis


Dosage :


  • Respiratory tract infection: 500 mg, 3 times daily for 5 days
  • Urinary tract infection: 500 mg, 4 times daily for 5 days
  • Gastrointestinal tract infection: 500 mg, 3 times daily minimum for 5 days


Children: 20-40 mg/kg body weight/day or according to the doctor’s instruction


Presentation and Registration Number :

GENICOL®-500 Box, 10 strips @ 10 capsule; DKL9608005101B1




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